Workflow
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Patient
ID: PAT001
Name: John Doe
Age: 63
Sex: Male
Diagnosis: NSCLC
Subtype: Adenocarcinoma
Notes: High-risk patient
Name: John Doe
Age: 63
Sex: Male
Diagnosis: NSCLC
Subtype: Adenocarcinoma
Notes: High-risk patient
Sample
Sample ID: SMP001
Type: Tumor
Tissue: Lung
Stage: IIIA
Grade: Moderately differentiated
Notes: RNA-seq prepared
Molecular Profile ID: MP001
Type: Tumor
Tissue: Lung
Stage: IIIA
Grade: Moderately differentiated
Notes: RNA-seq prepared
Molecular Profile ID: MP001
Molecular Profile
Mutations
EGFR: L858R
TP53: R273H
KRAS: G12C
TP53: R273H
KRAS: G12C
Expression
EGFR: 2.4
TP53: 1.0
KRAS: 1.8
TP53: 1.0
KRAS: 1.8
CNV
EGFR: Amplified
TP53: Normal
KRAS: Normal
TP53: Normal
KRAS: Normal
K2 Think Analysis
Genes Analyzed
EGFR: Oncogene, L858R
Predicted Response: Sensitive
Inhibitors: Erlotinib, Osimertinib
TP53: Tumor Suppressor, R273H
Predicted Response: Unknown
Predicted Response: Sensitive
Inhibitors: Erlotinib, Osimertinib
TP53: Tumor Suppressor, R273H
Predicted Response: Unknown
Summary
Primary Targets: EGFR, KRAS
Best Candidate: EGFR
Confidence Score: 0.87
Best Candidate: EGFR
Confidence Score: 0.87
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